Found: The dial in the brain that controls the immune system

https://www.nature.com/articles/d41586-024-01259-2

Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the periphery of the body and act as master regulators of the body’s inflammatory response.

doi: https://doi.org/10.1038/d41586-024-01259-2

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"title": "Found: The dial in the brain that controls the immune system",
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"author": "Giorgia Guglielmi",
"date": "2024-05-01T00:00:00.000Z",
"description": "Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.",
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"title": "Found: the dial in the brain that controls the immune system",
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"url": "https://www.nature.com/articles/d41586-024-01259-2",
"title": "Found: the dial in the brain that controls the immune system",
"description": "Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the...",
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"content": "<div>\n <article>\n <div>\n <p>Scientists have long known that <a target=\"_blank\" href=\"https://doi.org/10.1038/d41586-023-00509-z\">the brain plays a part in the immune system</a> — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-021-01396-y\">immune cues from the periphery of the body</a> and act as master regulators of the body’s <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-00871-6\">inflammatory response</a>.</p>\n <p><em>doi: https://doi.org/10.1038/d41586-024-01259-2</em></p>\n <div><h2 id=\"Bib1\">References</h2></div>\n <h2 id=\"related-articles\">Related Articles</h2>\n <ul>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-023-00509-z\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24096670.jpg\" />\n Your brain could be controlling how sick you get — and how you recover\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-022-01502-8\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24045344.jpg\" />\n Guardians of the brain: how a special immune system protects our grey matter\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-00169-7\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_26671374.jpg\" />\n Can autoimmune diseases be cured? Scientists see hope at last\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-023-00584-2\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24096666.jpg\" />\n Anxiety can be created by the body, mouse heart study suggests\n </a>\n </p>\n </li>\n</ul>\n <h2 id=\"subjects\">Subjects</h2>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/brain\">Brain</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/immunology\">Immunology</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/neuroscience\">Neuroscience</a>\n </li>\n</ul>\n <section>\n <h2 id=\"tablist-heading\">Latest on:</h2>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-0-container\">Brain</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-1-container\">Immunology</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-2-container\">Neuroscience</a>\n </li>\n </ul>\n <section>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02655-6\">\n <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02655-6/d41586-026-02655-6_53172328.gif\" />\n <p>Drug-delivering particles aim to breach the blood–brain barrier</p>\n <p><span>Outlook</span> <span>09 SEP 26</span></p>\n </a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02661-8\">\n <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02661-8/d41586-026-02661-8_53165450.jpg\" />\n <p>The brain struggles to make new neurons in people with depression</p>\n <p><span>News</span> <span>25 AUG 26</span></p>\n </a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02377-9\">\n <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02377-9/d41586-026-02377-9_53122980.jpg\" />\n <p>Psychedelics tune the brain to the environment</p>\n <p><span>News &amp; 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Associate Professor class focus on innovative research about ferroic smart materials or technology transfer</p>\n <p>Ningbo, Zhejiang (CN)</p>\n <p>Center for Advanced Smart Materials (CASM), Yongjiang Laboratory (Y-Lab)</p>\n </div>\n </div>\n <p><img src=\"https://www.nature.com/naturecareers/getasset/0cd3afbf-67a2-42c0-ac85-bd7a22d1059f/\" />\n </p>\n </li>\n <li>\n <div>\n <h4><a target=\"_blank\" href=\"https://www.nature.com/naturecareers/job/12864553/assistant-associate-professor-genomics/?TrackID=62&amp;utm_source=widget&amp;utm_medium=referral&amp;utm_campaign=62\">Assistant/Associate Professor (Genomics</a></h4>\n <div>\n <p>The Department of Biology in the College of Science, at the University of Texas at Arlington (UTA) (http://www.uta.edu/biology/),...</p>\n <p>University of Texas, Arlington</p>\n <p>University of Texas at Arlington, Department of Biology</p>\n </div>\n </div>\n </li>\n <li>\n <div>\n <h4><a target=\"_blank\" href=\"https://www.nature.com/naturecareers/job/12864547/news-intern-nature-news/?TrackID=62&amp;utm_source=widget&amp;utm_medium=referral&amp;utm_campaign=62\">News Intern, Nature News</a></h4>\n <div>\n <p>Job Title: News Intern, Nature News Location: Washington, D.C or New York — Hybrid Working Application Deadline: September 23, 2026   About Springe...</p>\n <p>Washington D.C.</p>\n <p>Springer Nature Ltd</p>\n </div>\n </div>\n <p><img src=\"https://www.nature.com/naturecareers/getasset/57a66c8c-df5e-4f83-871e-2daf68f37290/\" />\n </p>\n </li>\n <li>\n <p><img src=\"https://www.nature.com/naturecareers/getasset/e3cc705e-4b1a-4cad-9d99-7b8e49b85cd9/\" />\n </p>\n </li>\n </ul>\n </div>\n </div>\n </article>\n </div>",
"author": "Guglielmi, Giorgia",
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"published": "2024-05-01",
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